Steven F. Abcouwer

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University: 
University of Michigan - Ann Arbor
Unit: 
Medicine
Department: 
Ophthalmology and Visual Sciences, Kellogg Eye Center
Title: 
Associate Professor
Phone: 
734-232-8227
Short bio: 

Ph.D.

Recent publications: 

 

16. Abcouwer, S.F. "Neural inflammation and the microglial response in diabetic retinopathy." Journal of Ocular Biology, Diseases and Informatics, 4(1-2):25-33, 2012 

 

15. P.E. Fort, M.K. Losiewicz, C.E.N. Reiter, R.S.J. Singh, M. Nakamura, S.F. Abcouwer, A.J. Barber and  T.W. Gardner, Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: Evidence for retinal insulin resistance. PLoS ONE, 6(10):e26498, 201.

 

14. A.J. Barber, T.W. Gardner and S.F. Abcouwer. The significance of vascular and neural apoptosis to the pathology of diabetic retinopathy. Invest Ophthalmol Vis Sci 52(2): 1156-1163, 2011 

 

13. S.F. Abcouwer, C.-M. Lin, E.B., Wolpert, S. Shanmugam, E.W. Schaefer, W.M. Freeman, A.J. Barber, and D.A. Antonetti. Vascular permeability and apoptosis are separable processes in retinal ischemia-reperfusion injury: effects of ischemic preconditioning, bevacizumab and etanercept. Invest Ophthalmol Vis Sci. 51(11):5920-33, 2010

 

12. C.A. Aveleira, C.-M. Lin, S.F. Abcouwer, A.F. AmbrÌ_sio, D.A. Antonetti. TNF-ë± signals through PKCë¦/NF-ë¼B to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes 59(11):2872-82, 2010

Keywords: 
Diabetic Complications,
diabetic retinopathy,
Ischemia,
Microglia,
Neural Inflammation,
Neuroinflammation,
Neurodegeneration,
Vascular Permeability,
Leukostasis,
Bone Marrow-Derived Stem and Precursor Cells,
Flow Cytometry,
Alpha2A-Adrenergic Receptor (ADRA2A),
Adenosine A3 Receptor (ADORA3),
CCL2 (monocyte chemoattractent protein-1),
CX3CL1 (fractalkine)