Theodora Danciu

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University: 
University of Michigan - Ann Arbor
Unit: 
Dentistry
Department: 
Periodontics and Oral Medicine School of Dentistry
Title: 
Assistant Clinical Professor
Phone: 
763-2105
Short bio: 

 

Diplomate of the American Board of Oral and Maxillofacial Pathology, 2001

Certificate in Oral and Maxillofacial Pathology, Harvard University, 2000

D.M.Sc. in Oral Biology, Harvard University, 2000

D.M.D. , Harvard University, 1996

B.A. , Mathematics, University of California, Berkeley 1991

                                               

Research summary: 

My research focuses on the characterization of the oncogenic properties of the basic helix-loop-helix transcription factor Twist1 in head and neck squamous cell carcinoma (HNSCC) with the long-term objectives of identifying: (1) the roles played by Twist1 in regulating HNSCC function, (2) potential targets for therapeutic intervention and (3) a panel of markers that may be used to select optimal treatment for each patient.

Recent publications: 


Small ubiquitin-like modifier (SUMO) modification mediates function of the inhibitory domains of developmental regulators FOXC1 and FOXC2. Danciu TE, Chupreta S, Cruz O, Fox JE, Whitman M, Iñiguez-Lluhí JA. J Biol Chem. 2012 May 25;287(22):18318-29.

 

Receptor-interacting protein (RIP) and Sirtuin-3 (SIRT3) are on opposite sides of anoikis and tumorigenesis. Kamarajan P, Alhazzazi TY, Danciu T, D'silva NJ, Verdin E, Kapila YL. Cancer. 2012 Dec 1;118(23):5800-10.

 

Human very small embryonic-like cells generate skeletal structures, in vivo. Havens AM, Shiozawa Y, Jung Y, Sun H, Wang J, McGee S, Mishra A, Taichman LS, Danciu T, Jiang Y, Yavanian G, Leary E, Krebsbach PH, Rodgerson D, Taichman RS. Stem Cells Dev. 2013 Feb 15;22(4):622-30.

 

The soluble interleukin-6 receptor is a mediator of hematopoietic and skeletal actions of parathyroid hormone. Cho SW, Pirih FQ, Koh AJ, Michalski M, Matt E, Ritchie K, Sinder B, Oh S, Al-Dujaili SA, Lee J, Kozloff K, Danciu T, Wronski TJ, McCauley LK. J Biol Chem. 2013 Jan 7.

 

Degenerative alterations of the cementum-periodontal ligament complex and early tooth loss in a young patient with periodontal disease. Petruţiu SA, Buiga P, Roman A, Danciu T, Mihu CM, Mihu D. Rom J Morphol Embryol. 2012;53(4):1087-91.

 

Pediatric extranodal marginal zone B-cell lymphoma presenting as amyloidosis in minor salivary glands: a case report and review of the literature. Gabali A, Ross CW, Edwards PC, Schnitzer, B, and Danciu, TE. Accepted for publication 2012, Journal of Pediatric Oncology/Hematology.