Intravenous (IV) medication administration is critical for all patients undergoing care in a hospital setting. Inpatient hospital practice and emergency room visits require proper functional IVs as medications are most reliably delivered through IV route and having an IV in place can be life-saving in an emergency situation. Additionally, IV administration is by far the most common route of intraoperative drug delivery, and a functioning IV is crucial for surgical procedures to proceed. IV placement is most often attempted by trained nursing, anesthesia, surgical, or emergency personnel. Yet, despite training and experience, successful placement can be difficult requiring multiple attempts by multiple providers, additional specialized equipment, and placement of IVs smaller than the desired size. Studies have shown approximately one third of adult IV attempts are unsuccessful and a pediatric study found that approximately 40% of pediatric patients required 2-3 attempts before successful cannulation. IV attempts can cause discomfort and stress to the patient and multiple attempts only further the distress, increasing patient and provider anxiety. Smaller IVs (larger gauge) are significantly easier to place, and when a difficult attempt is anticipated or encountered a smaller IV may be placed with the hopes of obtaining larger access after initial successful placement. We propose using novel polymer technologies to create an intravenous catheter that begins at a smaller size and expands to a larger size when placed in a vein, creating an irreversible polymer expansion system. With such a product we give providers and patient the advantages small IV placement with the delivery benefits of a larger IV.