Recent work (Raabe 2015) provides evidence radiation induced cancers depend upon two factors: dose to DNA for initial damage and average dose rate to tissuesfor cancer promotion. A complete re-interpretation of prior data in radiation biology and cancer epidemiological studies necessitates refinement of the dose quantities to be on a physical scale that the relative doses to various tissue components is needed. List-mode Monte Carlo radiation transport codes will be used to investigate the spatial distribution of dose for external beams of gamma rays and neutrons, as well as due to internally depositted radionuclides. It is hoped that the work will explain discrepancies in relative biological effectiveness and models of low dose radiation health effects. If successful, the work invites both in vitro and in vivo animal experiments and epidemiological reanalysis of existing data.
$25,000 grant from Michigan Memorial Phoenix Project.
The Effects of Radiation and Emitted Light Transport on the Positional Response of 11 cm x 42.5 cm x 5.5 cm NaI(TI) Detectors
Submitted article in Health Physics Journal.