Recent data has emerged that enteric viruses are enhanced in their pathogenesis by commensal bacteria. Human noroviruses cause significant morbidity and mortality worldwide and infections are associated with significant economic costs. Interestingly, human norovirus binds to certain commensal and pathogeneic bacteria but the consequences of this interaction is unclear. In this cube, we propose collect human stool samples from symptomatic and asymptomatic individuals to determine whether i) the presence and density of particular Enterobacteriaceae species, and ii) additional microbial members are associated with specific clinical outcomes.
Epidemiological and Microbiome Associations between Klebsiella pneumoniae And Vancomycin- Resistant Enterococci Colonization in Intensive Care Unit Patients
Presented to the American Society for Microbiology/Microbe, Atlanta, GA