Ph.D., Purdue University
Faculty Recognition Award, 1998
Inventor Recognition, University of Michigan Technology Management, 1998
Alan McCall Award in Mass Spectrometry for best paper in journal "Organic Mass Spectrometry," 1993
Our laboratory is very interested in understanding the functional and organizational patterns underlying complex systems, i.e. to relate the proteome to the genome. A major focus has been the development of new technologies for comprehensive analysis of the responses of living cells to their environment at the molecular level, e.g. linking protein structure information to genome sequence. Thus a goal has been to achieve ultra-high throughput analysis of the majority of the proteins present in cells.
Falkner J, Andrews P. Fast tandem mass spectra-based protein identification regardless of the number of spectra or potential modifications examined. Bioinformatics. 2005 May 15; 21(10):2177-84. Ulintz PJ, Zhu J, Qin ZS, Andrews PC. Improved classification of mass spectrometry database search results using newer machine learning approaches. Mol Cell Proteomics. 2006 Mar;5(3):497-509. Epub 2005 Nov 30.
Falkner JA, Falkner JW, Andrews PC. ProteomeCommons.org JAF: reference information and tools for proteomics. Bioinformatics. 2006 Mar 1;22(5):632-3. Epub 2006 Jan 24.
Ostrom, PH, Gandhi, H, Strahler, JR, Walker, AK, Andrews, PC, Leykam, J, Stafford, TW, Kelly, RK, Walker, DN, Buckley, M and Humpula,J.: Unraveling the sequence and structure of the protein osteocalcin from a 42 ka fossil horse. Geochimica et Cosmochimica Acta. (in press)
Garcia BA, Joshi S, Thomas CE, Chitta RK, Diaz RL, Busby SA, Andrews PC, Ogorzalek Loo RR, Shabanowitz J, Kelleher NL, Mizzen CA, Allis CD, Hunt DF. Comprehensive Phosphoprotein Analysis of Linker Histone H1 from Tetrahymena thermophila.Mol Cell Proteomics. 2006 Sep;5(9):1593-1609. Epub 2006 Jul 10.
Ulintz PJ, Zhu J, Qin ZS, Andrews PC. Improved classification of mass spectrometry database search results using newer machine learning approaches. Mol Cell Proteomics. 2006 Mar;5(3):497-509. Epub 2005 Nov 30.
Jagtap P, Michailidis G, Zielke R, Walker AK, Patel N, Strahler JR, Driks A, Andrews PC, Maddock JR. Early events of Bacillus anthracis germination identified by time-course quantitative proteomics. Proteomics. 2006 Aug 23; [Epub ahead of print]
Jiang M, Datta K, Walker A, Strahler J, Bagamasbad P, Andrews PC, Maddock JR. The Escherichia coli GTPase CgtAE Is Involved in Late Steps of Large Ribosome Assembly. J Bacteriol. 2006 Oct;188(19):6757-70.
Kozarova A, Sliskovic I, Mutus B, Vacratsis PO, Simon ES, Andrews PC. Identification of Redox Sensitive Thiols of Protein Disulfide Isomerase Using Isotope Coded Affinity Technology and Mass Spectrometry. J Am Soc Mass Spectrom. 2006 Oct 27; [Epub ahead of print]
Falkner JA, Falkner JW, Andrews PC. ProteomeCommons.org IO Framework: reading and writing multiple proteomics data formats. Bioinformatics. 2007 Jan 15;23(2):262-3.