M.D., Saint Louis University School of Medicine
I have been engaged in biomedical research for nearly 30 years with a focus on bacterial infections of the airways in persons with cystic fibrosis. My laboratory has developed novel methods of bacterial genotyping to study the molecular epidemiology of CF related respiratory tract pathogens, as well as numerous genotype-based methods for the identification of respiratory tract pathogens. My work focusing on bacterial pathogenesis utilizes cell culture and animal models of infection. Recent research utilizes culture-independent microbial community profiling (including use of next generation DNA sequencing) to understand the lung microbiota in CF. My laboratory serves as a national reference laboratory for the Cystic Fibrosis Foundation, and maintains an extensive culture collection that includes approximately 35,000 strains of respiratory tract bacterial pathogens, including Burkholderia cepacia complex, Pseudomonas aeruginosa, Stenotrophomonas, Achromobacter, Haemophilus, Acinetobacter, and Staphylococcus spp. I am a member of the Michigan Nanotechnology Institute for Medicine and Biological Sciences and have investigated the use of novel nanoemulsions as antimicrobial agents. Another project involves NIH-funded research developing and employing microfabrication technology to advance our understanding of respiratory tract infection.
Carmody et al. Microbiome 3:12. 2015