Nick B. Langhals, Ph.D. serves as a Research Assistant Professor in the Plastic Surgery Section of the Department of Surgery and Assistant Research Scientist of Biomedical Engineering. Dr. Langhals received both his Master's of Science in Engineering (M.S.E. - 2003) as well as Doctor of Philosophy (Ph.D. - 2010) in Biomedical Engineering from the University of Michigan (Ann Arbor, MI, USA). His Bachelor's of Science in Engineering (B.S.E. - 2001) was obtained in Bioengineering from Arizona State University (Tempe, AZ, USA). Dr. Langhals has worked as a Senior Research Engineer within the Center for Neural Communication Technology and also served as a consultant for Neuronexus Technologies (Ann Arbor, MI) and Biotectix (Ann Arbor, MI).
Dr. Langhals' thesis efforts focused on the development and characterization of novel electrode designs as well as conductive polymer coatings to improve electrophysiological recordings from implanted cortical electrodes. Further, he also applied these technologies towards the development of signal processing algorithms and strategies to improve information extraction from cortical recordings. Dr. Langhals worked as a Senior Research Engineer within the Center for Neural Communication Technology where he was responsible for developing and coordinating all service, collaboration, and training activities of the CNCT for several years.
Johnson MD, Langhals NB, Kipke DR: Neural interface dynamics following insertion of hydrous iridium oxide microelectrode arrays. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 1: 3178-81, 2006. PM17947012
Escamilla-Mackert T, Langhals NB, Kozai TD, Kipke DR: Insertion of a three dimensional silicon microelectrode assembly through a thick meningeal membrane. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2009: 1616-8, 2009. PM19964007
Langhals NB, Kipke DR: Validation of a novel three-dimensional electrode array within auditory cortex. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2009: 2066-9, 2009. PM19964572
Ludwig KA, Miriani RM, Langhals NB, Joseph MD, Anderson DJ, Kipke DR: Using a common average reference to improve cortical neuron recordings from microelectrode arrays. Journal of neurophysiology 101(3): 1679-89, 2009. PM19109453
Rohatgi P, Langhals NB, Kipke DR, Patil PG: In vivo performance of a microelectrode neural probe with integrated drug delivery. Neurosurg Focus 27(1): E8, 2009. PM19569896
Urbanchek MG, Shim BS, Baghmanli Z, Wei B, Schroeder K, Langhals NB, Miriani RM, Egeland BM, Kipke DR, Martin DC, Cederna PS: Conduction Properties Of Decellularized Nerve Biomaterials. IFMBE proceedings 32: 430-433, 2010. PM21841944
Kozai TD, Marzullo TC, Hooi F, Langhals NB, Majewska AK, Brown EB, Kipke DR: Reduction of neurovascular damage resulting from microelectrode insertion into the cerebral cortex using in vivo two-photon mapping. Journal of neural engineering 7(4): 046011, 2010. PM20644246
Ludwig KA, Langhals NB, Joseph MD, Richardson-Burns SM, Hendricks JL, Kipke DR: Poly(3,4-ethylenedioxythiophene) (PEDOT) polymer coatings facilitate smaller neural recording electrodes. Journal of neural engineering 8(1): 014001, 2011. PM21245527
Seymour JP, Langhals NB, Anderson DJ, Kipke DR: Novel multi-sided, microelectrode arrays for implantable neural applications. Biomedical microdevices 13(3): 441-51, 2011. PM21301965
Ludwig KA, Miriani RM, Langhals NB, Marzullo TC, Kipke DR: Use of a Bayesian maximum-likelihood classifier to generate training data for brain-machine interfaces. Journal of neural engineering 8(4): 046009, 2011. PM21654038
Yoshida Kozai TD, Langhals NB, Patel PR, Deng X, Zhang H, Smith KL, Lahann J, Kotov NA, Kipke DR: Ultrasmall implantable composite microelectrodes with bioactive surfaces for chronic neural interfaces. Nature materials: 2012. PM23142839
TA Kung, RA Bueno, Langhals NB, MG Urbanchek, PS Cederna: Innovations in Prosthetic Interfaces for the Upper Extremity Plastic and Reconstructive Surgery In Press: ..., 2013.
EK Kim, KB Sugg, Langhals NB, SM Lightbody, ME Baltrusaitis, MG Urbanchek, PS Cederna, GJ Gerling: An engineered tactile afferent modulation platform to elicit compound sensory nerve action potentials in response to force magnitude World Haptics Conference (WHC) WHC.2013.6548415: 241 - 246, 2013.
Larson JV, Kung TA, Cederna PS, Sears ED, Urbanchek MG, Langhals NB: Clinical factors associated with replantation after traumatic major upper extremity amputation. Plastic and reconstructive surgery 132(4): 911-9, 2013. PM24076683