M.D. Tel Aviv University. 1986.
Emotional dysregulation (exaggerated or inappropriate emotional response) and inability to cognitively modulate this response, are the hallmarks of Psychiatric disorders like Posttraumatic stress disorder (PTSD), Phobia, and Depression. One of the main interests of our lab focuses on functional neuroanatomy of emotions of response to stress and trauma, and as it relates to pathophysiology of stress related disorders. We are investigating specific patterns of cognitive-emotional-somatic interaction and the underlying neurocircuitry in healthy controls and psychiatric patients, and the effects of abnormal interactions on emotional regulation and decision making processes.
Pitman R.K., Rasmusson A.M., Koenen K.C., Shin L.M., Orr S.P., Gilbertson M.W., Milad M.R., Liberzon I. 2012 Biology of Posttraumatic Stress Disorder. Nature Neuroscience . Published on line October 10 doi:10.1038/nrn3339
Ho, S-H., Gonzalez, R., Abelson J.L., Liberzon, I. (2012) Neurocircuits Underlying Cognition-Emotion Interaction in a Social Decision Making Context. Neuroimage. doi:10.1016/j.neuroimage.2012.07.017
Knox, D., Stout, S., Henderson, C., Liberzon, I. (2012) Glucocorticoid Receptors And Extinction Retention Deficits In The Single Prolonged Stress Model. Neuroscience. DOI: 10.1016/j.neuroscience.2012.07.047
Chua, H.F., Ho, S.S., Jasinska, A.J., Polk, T.A., Welsh, R.C., Liberzon, I. & Strecher, V.J. (2011) Self-related neural response to tailored smoking-cessation messages predicts quitting. Nat Neurosci. Apr;14(4):426-7. Epub 2011 Feb 27
Shin, L.M. &; Liberzon, I. (2009). "http://www.nature.com/npp/journal/vaop/ncurrent/full/npp200983a.html" The Neurocircuitry of Fear, Stress, and Anxiety Disorders Neuropsychopharmacology, 35(1):169-91 PMCID: PMC19625997
Sripada, C.S., Angstadt, M., Banks, S., Nathan, P.J., Liberzon, I. & Phan, K,L. (2009) Functional neuroimaging of mentalizing during the trust game in social anxiety disorder. Neuroreport, 15; 20(11): 984-9
Liberzon I, King AP, Britton JC, Phan KL, Abelson JA,Taylor SF: Paralimbic and Medial Prefrontal Cortical involvement in Neuroendocrine Responses to Traumatic Stimuli. Am. J. Psychiatry 2007 164: p. 1250-1258