Dr. Ivanova joined the Department of Neurology as an Assistant Research Professor in 2013. She completed her Ph.D. in the Institute of Molecular Biophysics at the Florida State University. Dr. Ivanova performed her postdoctoral research with Prof. David Eisenberg at the UCLA Molecular Biology Institute, where she then continued her scientific studies as a Research Associate.
She investigates the structure of amyloid aggregates, seeking to uncover the molecular basis of protein aggregation associated with various degenerative brain diseases including Amyotrophic Lateral Sclerosis (ALS), Parkinson’s and Alzheimer’s diseases. Dr. Ivanova’s present multi-disciplinary research focuses on molecular mechanisms of protein aggregation with the hope that we can find interventions that prevent, slow or reverse protein misfolding in amyloidogenic disorders.
Srabasti Acharya; Brian M. Safaie; Piriya Wongkongkathep; Magdalena I. Ivanova; Aida Attar; Frank-Gerrit Klärner; Thomas Schrader; Joseph A. Loo; Gal Bitan; Lisa J. Lapidus. Molecular basis for preventing α-synuclein aggregation by a molecular tweezer. Journal of Biological Chemistry. 2014;289(15):10727-10737.
Mark Whidden; Allison Ho; Magdalena I. Ivanova; Santiago Schnell. Competitive inhibition reaction mechanisms for the two-step model of protein aggregation. Biophysical Chemistry. 2014;193-194:9-19.
William F. Weiss IV; Aming Zhang; Magdalena I. Ivanova; Erinc Sahin; Jacob L. Jordan; Erik J. Fernandez; Christopher J. Roberts. Reduction of the C191-C220 disulfide of α-chymotrypsinogen A reduces nucleation barriers for aggregation. Biophysical Chemistry. 2014;185:79-87.