Education: University of Minnesota B.S. 1980; University of Minnesota Ph.D. 1985.
Professor Orr’s research centers on systems where the properties are controlled by the characteristics of surfaces or interfaces. As designed structures become ever smaller, their surface characteristics begin to influence, or even control, their behavior. Often the research involves scanning probe microscopies such as STM and AFM. Specific examples of research interests include: studies of molecules adsorbed on Si and Au surfaces; the molecular origin of negative differential resistance in metal-insulator-metal devices; the mechanism for composition modulation in compound semiconductors grown by molecular-beam epitaxy; and the development of multifunctional nanoparticles as therapeutics for cancer treatment.
Pascale Leroueil, Stassi DiMaggio, Abigail Leistra, Craig Blanchette, Christine Orme, Kumar Sinniah, Bradford G. Orr and Mark Banaszak Holl, “Characterization of Folic Acid and Poly(amidoamine) Dendrimer Interactions with Folate Binding Protein: A Force-Pulling Study”, J. of Phys. Chem. B Aug (2015). DOI: 10.1021/acs.jpcb.5b05391
Sriram Vaidyanathan, Kevin Anderson, Rachel Merzel, Binyamin Jacobivitz, Milan Kaushik, Christina Kelly, Mallory van Dongen, Casey Dougherty, Bradford G. Orr, Mark Banaszak Holl, “ Quantitative Measurement of Cationic Polymer Vector and Polymer/pDNA Polyplex Intercalation into the Cell Plasma Membrane”, ACS Nano (2015) DOI: 10.1021/acsnano.5b01263
Sriram Vaidyanathan, Bradford G. Orr, Mark Banaszak-Holl, "Detergent Induction of HEK 293A Cell Membrane Permeability Measured Under Quiescent and Superfusion Conditions using Whole Cell Patch Clamp", J. Phys. Chem. Part B. 118(8) 2112-2123, DOI: 10.1021/jp4124315 (2014)