2003, B.S. in Physics, University of Science and Technology of China
2009, Ph.D. in Physics, Massachusetts Institute of Technology
09/2009 – 09/2013, Postdoctoral Fellow, Stanford University, Stanford, CA; Department of Chemical & Systems Biology. Advisor: James E. Ferrell
09/2013 – 12/2013, Visiting Scholar, Harvard Medical School, Boston, MA; Department of Systems Biology. Collaborator: Sean Megason
The broad focus of the Yang lab is on the quantitative understanding of early embryo development, a complex pattern formation process that involves proliferation, differentiation, and migration of individual cells, and cell-cell communications through mechanical and chemical signaling. Our strategy is to connect these multi-scale mechanisms by developing complementary in vitro and in vivo systems in the vertebrate zebrafish (Danio rerio) embryos.
Q. Yang and J. E. Ferrell Jr.. The Cdk1-APC/C cell cycle oscillator circuit functions as a time- delayed, ultrasensitive switch. Nat Cell Biol 15, 519 (2013).
J. E. Ferrell Jr., T. Tsai, and Q. Yang. Modeling the cell cycle: why do certain circuits oscillate? Cell 144, 874 (2011).
Q. Yang, B. F. Pando, G. Dong, S. S. Golden, and A. van Oudenaarden. Circadian gating of the cell cycle revealed in single cyanobacterial cells. Science 327, 1522 (2010).
G. Dong, Q. Yang, Q. Wang, Y. Kim, T. L. Wood, K. W. Osteryoung, A. van Oudenaarden, and S. S. Golden. Elevated ATPase activity of KaiC applies a circadian checkpoint on cell division in Synechococcus elongatus. Cell 140, 529 (2010).
B. B. Kaufmann*, Q. Yang*, J. T. Mettetal, and A. van Oudenaarden. Heritable stochastic switching revealed by single-cell genealogy. PLoS Biol 5, e239 (2007).