Ph.D. Miami University, OH. 2001-2006; Research Fellow, Cincinnati Children's Hospital 2006-2011
Developmental Biology: Using model organisms to understand mechanisms by which the embryo develops, with a focus on specification, differentiation and organogenesis of tissue derived from the endoderm.
Stem Cell Biology and Regenerative Medicine: Directing differentiation of human pluripotent stem cells into different endodermal lineages such that we may generate tissue for replacement therapies and discover novel in vitro methods to model and study human development and disease.
McCracken KW et al. Nat Protoc. 2011 Nov 10;6(12):1920-8. PMID: 22082986
Spence JR et al. Nature. 2011 Feb 3;470(7332):105-9. PMID: 21151107
Spence JR et al. Dev Dyn. 2011 Mar;240(3):501-20. PMID: 21246663
Spence JR et al. Dev Cell. 2009 Jul;17(1):62-74. PMID: 19619492