My training is in fungal genetics and evolution.
1996 - B.S. Botany, University of Georgia
2003 - Ph.D. Biology, Duke University
Our lab pursues questions regarding the evolution of populations of fungi using molecular tools.
- Experimental evolution of virulence. Using a yeast-invertebrate model we are testing the role of mitotic recombination in pathogen adaptation.
- Phylogenomics of the fungal kingdom. By sequencing the genome of a species on the earliest branch of the fungal kingdom, we determined traits that define the kingdom.
- Environmental microbiology. An obscure group of fungi known as Cryptomycota are revealed by analysis of environmental samples using next generation sequencing.
Lazarus, K. L., and T. Y. James. (2015). “Surveying the biodiversity of the early-diverging fungal phylum Cryptomycota using a targeted PCR approach.” Fungal Ecol. 14: 62-70.
Seplyarskiy, V. B., M. A. Baranova, E. V. Leushkin, M. D. Logacheva, A. A. Penin, A. S. Kondrashov, and T. Y. James. (2014). “Crossing-over in a hypervariable species preferentially occurs in regions of high local similarity.” Mol. Biol. Evol. 31: 3016-3025.
Haag, K. L., T. Y. James, J.-F. Pombert, R. Larsson, T. M. M. Schaer, D. Refardt, and D. Ebert. (2014). “Evolution of a morphological novelty occurred before genome compaction in a lineage of extreme parasites.” Proc. Natl. Acad. Sci. U. S. A. 111: 15480-15485.
Shaw, S. D., L. Berger, S. Bell, S. Dodd, T. Y. James, L. F. Skerratt, P. J. Bishop, and R. Speare. (2014). “Baseline cutaneous bacteria of free-living New Zealand native frogs (Leiopelma archeyi and Leiopelma hochstetteri) and implications for their role in defense against the amphibian chytrid (Batrachochytrium dendrobatidis).” J. Wildlife Dis. 50: 723-732.
James, T. Y., S. Sun, W. Li, J. Heitman, H.-C. Kuo, Y.-H. Lee, F. O. Asiegbu, and Å. Olson. (2013). “Polyporales genomes reveal the genetic architecture underlying tetrapolar and bipolar mating systems.” Mycologia 105: 1374-1390.
Longcore, J. E. P. M. Letcher, and T. Y. James. (2011). “Homolaphlyctis polyrhiza gen. et sp. nov., a species in the Rhizophydiales (Chytridiomycetes) with multiple rhizoidal axes.” MycoTaxon 118: 433-440.