1990-1994 Kyoto University, Japan, B.S., Biology
1994-1999 Kyoto University, Japan, Ph.D., Biophysics with Dr. Mitsuhiro Yanagida
Thesis “Control of metaphase-anaphase progression by the Anaphase-promoting complex/cyclosome (APC/C).”
1999-2001 Kyoto University, Japan, Postdoctoral Fellow with Dr. Shunichi Takeda
Yukiko Yamashita uses the fruit fly Drosophila to study the impact of age on stem cell function and illuminate the mechanisms underlying the loss of control over stem cell division, which is regarded as the primary cause of many human diseases.
Pelletier, L. and Y. M. Yamashita (2012). "Centrosome asymmetry and inheritance during animal development." Curr Opin Cell Biol.
Roth, T. M., C. Y. Chiang, et al. (2012). "Centrosome misorientation mediates slowing of the cell cycle under limited nutrient conditions in Drosophila male germline stem cells." Mol Biol Cell 23(8): 1524-1532.
Yuan, H., C. Y. Chiang, et al. (2012). "Regulation of cyclin A localization downstream of Par-1 function is critical for the centrosome orientation checkpoint in Drosophila male germline stem cells." Dev Biol 361(1): 57-67.
Inaba, M., H. Yuan, et al. (2011). "String (Cdc25) regulates stem cell maintenance, proliferation and aging in Drosophila testis." Development 138(23): 5079-5086.
Pereira, G. and Y. M. Yamashita (2011). "Fly meets yeast: checking the correct orientation of cell division." Trends Cell Biol 21(9): 526-533.
Yadlapalli, S., J. Cheng, et al. (2011). "Drosophila male germline stem cells do not asymmetrically segregate chromosome strands." J Cell Sci 124(Pt 6): 933-939.
Cheng, J., A. Tiyaboonchai, et al. (2011). "Asymmetric division of cyst stem cells in Drosophila testis is ensured by anaphase spindle repositioning." Development 138(5): 831-837.